Early impairment of cognitive functions in Parkinson's disease

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Early impairment of cognitive functions in Parkinson's disease.

BACKGROUND Impairment in non-motor functions such as disturbances of some executive functions are also common events in Parkinson's disease patients. OBJECTIVE To verify the performance of Parkinson's disease patients in activities requiring visuoconstructive and visuospatial skills. METHOD Thirty elderly patients with mild or moderate stages of Parkinson's disease were studied. The assessm...

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Predictors of Mild Cognitive Impairment in Early-Stage Parkinson's Disease

AIM The aim of this study was to identify mild cognitive deficits in Parkinson's disease (PD) prior to extensive neurodegeneration and to evaluate the extent to which dopamine depletion and other disease-related predictors can explain cognitive profiles. METHODS Neuropsychological performances of 40 nondemented early-stage PD patients and 42 healthy controls were compared across on or off dop...

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Anatomical Correlates of Cognitive Functions in Early Parkinson's Disease Patients

BACKGROUND Cognitive deficits may occur early in Parkinson's disease (PD) but the extent of cortical involvement associated with cognitive dysfunction needs additional investigations. The aim of our study is to identify the anatomical pattern of cortical thickness alterations in patients with early stage PD and its relationship with cognitive disability. METHODS We recruited 29 PD patients an...

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Mild cognitive impairment represents early-stage Alzheimer disease.

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ژورنال

عنوان ژورنال: Arquivos de Neuro-Psiquiatria

سال: 2007

ISSN: 0004-282X

DOI: 10.1590/s0004-282x2007000300008